ChemMedChem 9: 657C664, 2014. also repressed TGF1-induced appearance of profibrotic substances such as for example fibronectin and elevated appearance of antifibrotic substances such as for example peroxisome proliferator-activated receptor- (PPAR). Chromatin immunoprecipitation quantitative PCR using an antibody against H3K27ac (histone H3 acetylated at lysine 27; a known HDAC8 substrate and a marker for energetic enhancers) … Continue reading ChemMedChem 9: 657C664, 2014